Frequently asked questions
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Product Information
Immun’Âge is a natural, non-GMO food supplement 100% made from fermented papaya (FPP®).
It is gluten-free, additive-free, gentle, clinically tested and with no detected
side effects for the last 30 years.
Immun’Âge is Clean, Safe, and Proven
Simply dissolve the contents of one sachet under the tongue, no need for water, easy & tasty!
It is best to take Immun’Âge on an empty stomach. Taking it first thing in the morning or just before going to bed are the best times.
Do not eat or drink anything within five minutes of taking Immun’Âge.
Our Fermented Papaya Preparation (FPP) is obtained after a 10-month fermentation process in Japan, which gives it its exceptional properties.
The recommended dosage of Immun'Âge 100% FPP is 1 packet per day for healthy aging.
For specific pathologies and conditions, please contact us at contact@immunage.com to adapt your dosage.
Many studies conducted all over the world by renowned scientists show that Immun’Âge® is not associated with any side effects, and presents no risks.
In 25 years more than ten million Immun’Âge packets were sold without any report on safety-related problems.
Many people do take Immun’Âge daily. Intake may vary depending on your condition, your needs and your response to the product.
The standard daily intake for an average healthy person for general health maintenance is one packet per day. (One box of Immun’Âge Classic contains 30 packets of 3 grams each.)
Immun'Âge can be used for children as a dietary supplement even in the case of recurrent ear, nose and throat infections commonly treated with antibiotics, but it should not replace any medical treatment.
Consulting your doctor is highly recommended for such infections.
- Children under one year of age (after weaning): Dilute half a packet in mineral water or milk, 2 to 3 times a week.
- Children up to six years: Place half a packet under the tongue once a day.
- Children over six years: Place one packet under the tongue once a day
After more than 25 years of commercialization worldwide, no side effect has ever been reported.
If you have a specific condition, please contact us and check with your health provider before taking Immun'Âge.
Immun’Âge is an all natural dietary supplement. There is no known or reported drug interaction to this day.
If you have a specific condition, please contact us and check with your health provider before taking Immun'Âge.
Benefits
- Reducing oxidative stress by supporting the body’s own antioxidants such as Glutathione and SOD.
- Strengthening immune balance and recovery for greater resilience against daily challenges.
- Enhancing cellular regeneration to help tissues and organs function optimally.
- Boosting ATP production at the cellular level — providing steady, natural energy where your body needs it most.
- Supporting cellular longevity by helping protect and elongate telomeres.
- Improving skin hydration, suppleness, and natural glow.
- Soothing inflammation that accelerates aging and discomfort.
- Promoting cognitive clarity and overall healthy aging.
Together, these properties work in synergy to support vitality, resilience, and graceful aging — helping you stay energized, focused, and radiant at every stage of life.
Backed by more than 30 clinical trials conducted over the past three decades.
Immun’Âge activates a key cellular system called the Nrf2 pathway — a master switch that drives the body’s natural defense and repair functions. You don’t need to remember the name; what matters is that it plays a vital role in maintaining long-term health.
When activated by Immun’Âge, the Nrf2 pathway switches on hundreds of genes in each cell, prompting the body to produce its own antioxidants and detoxifying enzymes, powerful tools for defense, repair, and renewal.
This cellular activation helps reduce inflammation, neutralize toxins, and slow the visible and internal effects of aging.
- Fresh papaya contains, among others, vitamin A and C, along with papain, a digestive enzyme that is found in the latex (between the bark and the pulp of the fruit).
- The fermentation process to produce FPP® eliminates these vitamins. FPP® doesn’t contain papain either because it is made with only the pulp of the fruit.
- Fermentation causes a modification of the constituents of fresh papaya, which results in 2 distinct foods, both in their composition and properties.
With age, the immune system is less effective, oxidative stress increases and the production of cellular energy (ATP) decreases.
When it comes to the immune system, Immun'Âge stimulates immunity by activating macrophages, NK cells (Natural Killer) and the production of NO (Nitric Oxide) which are used for immune defence.
Regarding the antioxidant system, Immun'Âge stimulates the main endogenous antioxidative enzymes: superoxide dismutase (SOD, main antioxidative enzyme in the body), glutathione peroxidase, catalase...; making your whole antioxidative system work better from within.
Immun'Âge also allows, to a lesser extent, to directly capture free radicals (measured thanks to observation by ESR = allowing us to see the capture of free radicals).
Over the years, the production of cellular energy (ATP) decreases in your body.
Concerning the production of cellular energy, Immun'Âge makes it possible to stimulate the production of ATP at the cellular level (via the Krebs cycle): the sugars contained in Immun'Âge enter the cell without the need for insulin and make it possible to produce ATP (an energy unit molecule derived from sugars).
Special conditions
No, Immun’Âge is gluten-free
Carbohydrates, including natural sugars from fruit, are one of the body's primary source of energy. To meet the daily energy requirement of 2,000 calories, an average human body needs about 275 grams of carbohydrates.
A packet of Immun'Âge, contains 2.7 grams of carbohydrates and only represents 1% of the daily intake.
We have not carried out any specific study targeting pregnant women taking Immun’Âge.
However, in more than twenty years of research, there has been no report on side effect or toxicity of our product, even on women taking Immun’Âge during their pregnancy.
If you are pregnant, consult your health provider before taking Immun'Âge.
Immun’Âge can help keep a good vascular health by protecting the body against the dysfunction of the inner lining of the blood vessels and improving flexibility of the endothelium.
Clinical studies have shown a reassuring safety profile for Immun’Âge. In an eight-week placebo-controlled study, researchers reported no serious adverse effects or adverse changes in routine blood chemistry.
People taking anticoagulants, such as warfarin (Coumadin), acenocoumarol (Sintrom), or fluindione (Préviscan), need to maintain stable blood clotting levels, monitored through an INR blood test. Changes in diet or the introduction of supplements can sometimes affect these levels, making regular monitoring important.
We always recommend consulting your healthcare provider before taking Immun’Âge if you are undergoing anticoagulant treatment. Your doctor may recommend additional INR monitoring to ensure your treatment remains properly balanced.
Scientific reference: Effects of Fermented Papaya Preparation (FPP) on Safety Outcomes in Older Adults — Journal of Frailty & Aging, 2018.
Immun’Âge helps relieve the symptoms for people suffering from electro-sensitivity. It helps them recover a normal brain perfusion and reduce some of the clinical symptoms (tachycardia, fatigue…).
You an find more information on this page.
Osato International was granted the US patent N° US 10.993.980 B2 for “METHOD FOR TREATING ELECTROHYPERSENSITIVITY WITH A FERMENTED PAPAYA PREPARATION”
Immun'Âge's fermentation is done using specific traditional yeasts (Saccharomyces), and after several months of fermentation, there are no living yeasts and identifiable yeast products anymore in Immun'Âge.
Over the past 25 years, people with yeast allergy did not encounter any problems while taking Immun'Âge.
However, since Immun'Âge's main components are carbohydrates (more specifically beta-glucans-like products) and amino acids, which are part of our cells components, allergy could occur, even if the risk is very low.
If you know that you have an allergy to yeast, we recommend testing Immun’Âge by taking half a packet to detect any possible allergic reactions.
Immun’Âge (FPP®) has been studied for its effects on the body's natural antioxidant defenses, including preliminary research exploring its potential role in supportive care following radiotherapy. Some chemotherapy and radiotherapy treatments work by generating oxidative stress to damage cancer cells. Because antioxidant products may interfere with this process, you should not take Immun’Âge during treatment unless specifically approved by your oncologist.
If you are considering Immun’Âge before treatment or for your recovery afterward, we always recommend consulting your oncology team to determine the appropriate timing and dosage.
If you experience dry mouth or difficulty taking the powder, Immun’Âge can be dissolved in water.
Scientific reference: Korkina et al., Radioprotective and Antioxidant Effects of Zinc Aspartate and Fermented Papaya Preparation FPP in Children with Acute Myelo-Lympholeukemia, 1995.
We always recommend talking to your health provider.
Immun’Âge helps reduce the oxidative phenomenon which takes place soon after alcohol withdrawal, to help protect the liver.
Supporting your body's natural immune defenses is one of Immun’Âge's primary purposes. It helps reinforce a healthy, balanced immune response and supports your body's resilience to everyday stress.
We always recommend consulting your healthcare provider if you have any specific medical conditions or are undergoing medical treatment.
Immun’Âge helps reduce the oxidative stress that may trigger complications after a gastritis, especially in older adults.
For any additional question, you can contact us at contact@immunage.com, we will be happy to assist you.